Kligman’s Modified Depigmenting Crème

₦23,900.00

Additional information

Ziora Kligman’s Modified Depigmenting Crème is a prescription-strength treatment combining Hydroquinone, Kojic Acid, Tretinoin and Dexamethasone to help manage stubborn pigmentation concerns, including melasma and post-inflammatory hyperpigmentation.

℞ Prescription Required
Ziora Prescription Skin Treatment

Kligman’s Modified Depigmenting Crème

Targeted Care for Stubborn Pigmentation

Stubborn dark spots? Get the right treatment. Not all pigmentation responds to regular brightening serums.

A prescription-strength treatment combining Hydroquinone, Kojic Acid, Tretinoin and Dexamethasone to help manage stubborn pigmentation concerns, including melasma and post-inflammatory hyperpigmentation.

Designed for use under professional supervision as part of a targeted treatment plan.

Stubborn Dark Spots
Melasma
Post-Acne Marks

What It Helps With

Targeted Pigmentation Care

◉

Stubborn Dark Spots

Helps reduce excess pigmentation in affected areas.

◐

Melasma

May be prescribed to manage certain types of melasma following professional assessment.

✧

Post-Acne Marks

Helps improve post-inflammatory hyperpigmentation associated with previous breakouts.

◈

Uneven Skin Tone

Supports a more even-looking complexion over time.

Key Active Ingredients

Four Actives. One Targeted Treatment.

5%

Hydroquinone

A depigmenting agent that reduces melanin production to help treat hyperpigmentation.

2%

Kojic Acid

Helps inhibit tyrosinase, an enzyme involved in melanin production.

0.02%

Tretinoin

A prescription retinoid that promotes skin cell turnover and supports pigmentation treatment.

0.1%

Dexamethasone

A corticosteroid included to reduce inflammation. Because topical steroids can cause significant adverse effects, its use must be medically supervised and time-limited.

Also contains: Alpha-Bisabolol and Vitamin E for antioxidant and skin-conditioning support.

Who Is It For?

For Prescribed Use Only

This treatment may be prescribed for people experiencing:

  • Persistent dark patches
  • Melasma
  • Post-inflammatory hyperpigmentation
  • Pigmentation that hasn’t responded to regular cosmetic skincare
This is not a general brightening cream or a product for changing your natural skin colour. A qualified prescriber must determine whether it is suitable for your skin.

How To Use

Use Only as Prescribed

1

Cleanse

Use a gentle facial cleanser.

2

Apply Treatment

Apply to the prescribed areas at night, using only the amount and frequency directed by your healthcare professional.

3

Moisturise

Use a suitable moisturiser as advised to support skin comfort.

4

Protect

Apply broad-spectrum SPF 30+ every morning and practise sun protection throughout the day.

Do not combine with other retinoids, exfoliating acids or irritating treatments unless specifically directed.
⚠ Important Safety Information

Do not use during pregnancy or while planning pregnancy. Seek medical advice regarding breastfeeding.

Not for continuous or indefinite use. Treatment duration must be set by your prescriber, with medical review.

Full safety information and possible side effects

This formula contains hydroquinone, tretinoin and a topical corticosteroid.

Possible adverse effects include redness, peeling, burning, irritation, acne-like eruptions and changes in pigmentation.

Prolonged or inappropriate use can cause skin thinning, steroid-related side effects and, with hydroquinone, exogenous ochronosis.

Treatment duration must be determined by your prescriber. Do not use continuously or indefinitely without medical review.

FAQs

Frequently Asked Questions

Can I use this crème for ordinary dark spots?

Not every dark spot needs prescription treatment. A professional assessment will help determine whether this formula is appropriate.

Can I use it every night?

Only according to your prescribed treatment schedule.

Can I combine it with Ziora BHA + Mandelic Serum?

Do not combine them without professional guidance because of the increased risk of irritation.

How long before I see results?

Improvement varies according to the type and depth of pigmentation. Your prescriber should monitor your response and determine when to stop or change treatment.

Can I use it long-term?

It is not intended for indefinite continuous use. The corticosteroid and hydroquinone require particular caution.

Do I need sunscreen?

Yes. Consistent sun protection is essential for pigmentation management.

Full Ingredient List

View all ingredients

Active Ingredients: Hydroquinone 5%, Kojic Acid 2%, Tretinoin 0.02%, Dexamethasone 0.1%

Other Ingredients: Aqua (Water), Cetearyl Alcohol (and) Sodium Lauryl Sulfate (Emulsifying Wax BP), Bisabolol, Camellia Sinensis Extract, Tocopherol, Propanediol, Glycerin, Phenoxyethanol, Ethylhexylglycerin.

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